Baseline reward circuitry activity and trait reward responsiveness predict expression of opioid analgesia in healthy subjects.
Variability in opioid analgesia has been attributed to many factors. For example, genetic variability of the μ-opioid receptor (MOR)-encoding gene introduces variability in MOR function and endogenous opioid neurotransmission. Emerging evidence suggests that personality trait related to the experien...
Principais autores: | Wanigasekera, V, Lee, M, Rogers, R, Kong, Y, Leknes, S, Andersson, J, Tracey, I |
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Formato: | Journal article |
Idioma: | English |
Publicado em: |
2012
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