Recognition of dimethylarginine analogues by tandem Tudor domain protein Spindlin1

Epigenetic readout of the combinatorial posttranslational modification comprised of trimethyllysine and asymmetric dimethylarginine (H3K4me3R8me2a) takes place via biomolecular recognition of tandem Tudor-domain-containing protein Spindlin1. Through comparative thermodynamic data and molecular dynam...

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Detalhes bibliográficos
Main Authors: Porzberg, MRB, Moesgaard, L, Johansson, C, Oppermann, U, Kongsted, J, Mecinović, J
Formato: Journal article
Idioma:English
Publicado em: MDPI 2022