Modafinil for the treatment of fatigue in lung cancer: results of a placebo-controlled, double-blind, randomized trial.

Modafinil for the treatment of fatigue in lung cancer: results of a placebo-controlled, double-blind, randomized trial.

Show other versions (1)

PURPOSE: Fatigue is a distressing symptom occurring in more than 60% of patients with cancer. The CNS stimulants modafinil and methylphenidate are recommended for the treatment of cancer-related fatigue, despite a limited evidence base. We aimed to evaluate the efficacy and tolerability of modafinil...

Full description

Bibliographic Details
Main Authors:	Spathis, A, Fife, K, Blackhall, F, Dutton, S, Bahadori, R, Wharton, R, O'Brien, M, Stone, P, Benepal, T, Bates, N, Wee, B
Format:	Journal article
Language:	English
Published:	American Society of Clinical Oncology 2014

Similar Items

Modafinil for the treatment of fatigue in lung cancer: results of a placebo-controlled, double-blind, randomized trial
by: Spathis, A, et al.
Published: (2014)

A multicenter, randomized, double-blinded, placebo-controlled trial of modafinil for lung cancer-related fatigue: Dose response and patient satisfaction data.
by: Fife, K, et al.
Published: (2013)

Modafinil for multiple sclerosis fatigue: does it work?
by: Littleton, E, et al.
Published: (2010)

Effects of Modafinil on Sleep Pattern during Methamphetamine Withdrawal: A Double-blind Randomized Controlled Trial
by: Seyed Mohamad Moosavi, et al.
Published: (2019-07-01)

Short- and Long-Term Efficacy of Modafinil at Improving Quality of Life in Stroke Survivors: A Post Hoc Sub Study of the Modafinil in Debilitating Fatigue After Stroke Trial
by: Thomas P. Lillicrap, et al.
Published: (2018-04-01)

An audit of the use of Modafinil in clinical practice for the treatment of fatigue in multiple sclerosis patients
by: Littleton, E, et al.
Published: (2005)

Assessing the impacts of L-carnitine and modafinil on fatigue in Iraqi multiple sclerosis patients
by: Ahmed Hamza Al-Shammari, et al.
Published: (2023-01-01)

Effects of previous carbohydrate supplementation on muscular fatigue: double-blind, randomized, placebo-controlled crossover study
by: Rafael A. Battazza, et al.

Use of Modafinil in Psychiatric Disorders
by: Mehmet Hanifi Kokacya, et al.
Published: (2016-03-01)

Modafinil and Learning and Memory- Is there a Connection? Evaluation of the Effect of Modafinil on Learning and Memory in Wistar Rats
by: Mnnat Gill, et al.
Published: (2019-10-01)

Quetiapine and rivastigmine and cognitive decline in Alzheimer's disease: randomised double blind placebo controlled trial.
by: Ballard, C, et al.
Published: (2005)

Comparison of effects of modafinil and caffeine on fatigue-vulnerable and fatigue-resistant aircrew after a limited period of sleep deprivation
by: Yara Q. Wingelaar-Jagt, et al.
Published: (2024-01-01)

Randomized, Double‐Blind, Placebo‐Controlled, Single Ascending Dose Trial of Synthetic Preimplantation Factor in Autoimmune Hepatitis
by: Christopher B. O’Brien, et al.
Published: (2018-10-01)

Armodafinil versus Modafinil in Patients of Excessive Sleepiness Associated with Shift Work Sleep Disorder: A Randomized Double Blind Multicentric Clinical Trial
by: D. V. Tembe, et al.
Published: (2011-01-01)

Modafinil-induced Fixed Drug Eruption
by: Girish Vasant Gaikwad, et al.
Published: (2012-01-01)

Randomized, double-blinded, placebo-controlled pilot study: efficacy of faecal microbiota transplantation on chronic fatigue syndrome
by: Tapani Salonen, et al.
Published: (2023-07-01)

Efficacy and safety of bupropion in cancer-related fatigue, a randomized double blind placebo controlled clinical trial
by: Ebrahim Salehifar, et al.
Published: (2020-02-01)

Modafinil-Induced Increases in Brain Dopamine Levels
by: J Gordon Millichap
Published: (2009-04-01)

Modafinil Trial in Attention Deficit Hyperactivity Disorder
by: J Gordon Millichap
Published: (2005-12-01)

Modafinil decreases anxiety-like behaviour in zebrafish
by: Adrian Johnson, et al.
Published: (2017-02-01)

A double-blind placebo needle for acupuncture research
by: Takakura Nobuari, et al.
Published: (2007-10-01)

The use of modafinil for the treatment of fatigue in multiple sclerosis: A systematic review and meta‐analysis of controlled clinical trials
by: Shamas Ghazanfar, et al.
Published: (2024-07-01)

Efficacy of modafinil on fatigue and excessive daytime sleepiness associated with neurological disorders: a systematic review and meta-analysis.
by: Ping Sheng, et al.
Published: (2013-01-01)

Effectiveness of Korean Red Ginseng on fatigue in patients with rheumatic diseases: a randomized, double-blind, placebo-controlled study
by: Soo-Kyung Cho, et al.
Published: (2024-07-01)

Efficacy and Safety of "URSA Complex" in Subjects with Physical Fatigue: A Multicenter, Randomized, Double-blind, Placebo-controlled Trial
by: Kwang-Min Kim, et al.
Published: (2016-01-01)

Effects of MaquiBright® on improving eye dryness and fatigue in humans: A randomized, double-blind, placebo-controlled trial
by: Shin-ichiro Yamashita, et al.
Published: (2019-07-01)

A double-blind, placebo-controlled, randomized, clinical trial of the TLR-3 agonist rintatolimod in severe cases of chronic fatigue syndrome.
by: David R Strayer, et al.
Published: (2012-01-01)

Effect of Melatonin Plus Zinc Supplementation on Fatigue Perception in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial
by: Jesús Castro-Marrero, et al.
Published: (2021-06-01)

Double-Blind, Placebo-Controlled Study of Myotoxicity and Neurotoxicity of Bupivacaine in Rats
by: R. E. Lakhin, et al.
Published: (2019-11-01)

Effect of Vitamin A Supplementation on Fatigue and Depression in Multiple Sclerosis Patients: A Double-blind Placebo-controlled Clinical Trial
by: Sama Bitarafan, et al.
Published: (2016-01-01)

Effect of soy lecithin on fatigue and menopausal symptoms in middle-aged women: a randomized, double-blind, placebo-controlled study
by: Asuka Hirose, et al.
Published: (2018-01-01)

Effects of modafinil on emotional processing in first episode psychosis.
by: Scoriels, L, et al.
Published: (2011)

Microwave coprocessing of modafinil with Gelucire®: Thermal and compression characteristics
by: Derar Omari, et al.
Published: (2025-01-01)

Simple Synthesis of Modafinil Derivatives and Their Anti-inflammatory Activity
by: Mankil Jung, et al.
Published: (2012-09-01)

The successful treatment of hypercapnic respiratory failure with oral modafinil
by: Parnell H, et al.
Published: (2014-04-01)

Waking up to modafinil in shift work sleep disorder
by: Dilip Gude
Published: (2011-01-01)

An analytical review on probable anti-parkinsonian effect of modafinil
by: Mehdi Farhoudi, et al.
Published: (2013-12-01)

Double-blind clonazepam vs placebo in panic disorder treatment
by: ALEXANDRE MARTINS VALENÇA, et al.
Published: (2000-12-01)

Adjunctive aripiprazole in risperidone-induced hyperprolactinaemia: double-blind, randomised, placebo-controlled trial
by: G. Raghuthaman, et al.
Published: (2015-10-01)

A randomised double-blind placebo-controlled feasibility trial of flavonoid-rich cocoa for fatigue in people with relapsing and remitting multiple sclerosis
by: Coe, S, et al.
Published: (2019)