Modelling acidosis and the cell cycle in multicellular tumour spheroids

Modelling acidosis and the cell cycle in multicellular tumour spheroids

A partial differential equation model is developed to understand the effect that nutrient and acidosis have on the distribution of proliferating and quiescent cells and dead cell material (necrotic and apoptotic) within a multicellular tumour spheroid. The rates of cell quiescence and necrosis depen...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoirí:	Tindall, M, Dyson, L, Smallbone, K, Maini, P
Formáid:	Journal article
Foilsithe / Cruthaithe:	Elsevier 2012

Míreanna comhchosúla

Modelling the cell cycle and cell movement in multicellular tumour spheroids.
de réir: Tindall, M, et al.
Foilsithe / Cruthaithe: (2007)

Multicellular ovarian cancer spheroids: novel 3D model to mimic tumour complexity
de réir: Inken Flörkemeier, et al.
Foilsithe / Cruthaithe: (2024-10-01)

The potentiality of Citral in targeting breast cancer multicellular tumour spheroids (MTS)
de réir: Rusli, Muhammad Ehsan Fitri, et al.
Foilsithe / Cruthaithe: (2022)

A Hybrid Cellular Automata Model of Multicellular Tumour Spheroid Growth in Hypoxic Microenvironment
de réir: Yan Cai, et al.
Foilsithe / Cruthaithe: (2013-01-01)

Optical coherence tomography complements confocal microscopy for investigation of multicellular tumour spheroids
de réir: Neelam Hari, et al.
Foilsithe / Cruthaithe: (2019-07-01)

The Efficacy of Zinc Phthalocyanine Nanoconjugate on Melanoma Cells Grown as Three-Dimensional Multicellular Tumour Spheroids
de réir: Nkune Williams Nkune, et al.
Foilsithe / Cruthaithe: (2023-08-01)

Changes in P-glycoprotein activity are mediated by the growth of a tumour cell line as multicellular spheroids
de réir: Raúl Barrera-Rodríguez, et al.
Foilsithe / Cruthaithe: (2005-07-01)

Single cell organization and cell cycle characterization of DNA stained multicellular tumor spheroids
de réir: Karl Olofsson, et al.
Foilsithe / Cruthaithe: (2021-08-01)

Multimodal Mass Spectrometry Imaging of an Osteosarcoma Multicellular Tumour Spheroid Model to Investigate Drug-Induced Response
de réir: Sophie M. Pearce, et al.
Foilsithe / Cruthaithe: (2024-05-01)

An agent-based model for drug-radiation interactions in the tumour microenvironment: Hypoxia-activated prodrug SN30000 in multicellular tumour spheroids.
de réir: Xinjian Mao, et al.
Foilsithe / Cruthaithe: (2018-10-01)

Modeling tumor cell adaptations to hypoxia in multicellular tumor spheroids
de réir: Stephen Riffle, et al.
Foilsithe / Cruthaithe: (2017-08-01)

Quiescence as a mechanism for cyclical hypoxia and acidosis
de réir: Smallbone, K, et al.
Foilsithe / Cruthaithe: (2007)

Quiescience as a mechanism for cyclical hypoxia and acidosis
de réir: Smallbone, K, et al.
Foilsithe / Cruthaithe: (2007)

Quiescence as a mechanism for cyclical hypoxia and acidosis.
de réir: Smallbone, K, et al.
Foilsithe / Cruthaithe: (2007)

Modelling of tumour metabolism
de réir: Maini, P, et al.
Foilsithe / Cruthaithe: (2010)

Down-regulation of DNA mismatch repair enhances initiation and growth of neuroblastoma and brain tumour multicellular spheroids.
de réir: Samuel L Collins, et al.
Foilsithe / Cruthaithe: (2011-01-01)

Mathematical modelling of tumour acidity.
de réir: Smallbone, K, et al.
Foilsithe / Cruthaithe: (2008)

Mathematical modelling of tumour acidity
de réir: Smallbone, K, et al.
Foilsithe / Cruthaithe: (2008)

Gold Standard Hypoxia Marker? A Comparison of Pimonidazole and EF5 Kinetics in Multicellular Tumour Spheroids
de réir: Kelly, C, et al.
Foilsithe / Cruthaithe: (2010)

Heterotypic Multicellular Spheroids as Experimental and Preclinical Models of Sprouting Angiogenesis
de réir: Igor V. Vakhrushev, et al.
Foilsithe / Cruthaithe: (2021-12-01)

Episodic, transient systemic acidosis delays evolution of the malignant phenotype: Possible mechanism for cancer prevention by increased physical activity
de réir: Smallbone, K, et al.
Foilsithe / Cruthaithe: (2010)

Episodic, transient systemic acidosis delays evolution of the malignant phenotype: Possible mechanism for cancer prevention by increased physical activity.
de réir: Smallbone, K, et al.
Foilsithe / Cruthaithe: (2010)

Protocol for generation of multicellular spheroids through reduced gravity
de réir: Dylan A. Zinn, et al.
Foilsithe / Cruthaithe: (2023-06-01)

Multicellular Tumor Spheroids in Nanomedicine Research: A Perspective
de réir: Martina Rossi, et al.
Foilsithe / Cruthaithe: (2022-06-01)

Challenges of applying multicellular tumor spheroids in preclinical phase
de réir: Se Jik Han, et al.
Foilsithe / Cruthaithe: (2021-03-01)

Chemosensitivity of radioresistant cells in the multicellular spheroids of A549 lung adenocarcinoma
de réir: Huang Gang, et al.
Foilsithe / Cruthaithe: (2009-06-01)

Multicellular Tumour Spheroid as a model for evaluation of [<sup>18</sup>F]FDG as biomarker for breast cancer treatment monitoring
de réir: Josephsson Raymond, et al.
Foilsithe / Cruthaithe: (2006-03-01)

Investigating the steady state of multicellular spheroids by revisiting the two-fluid model
de réir: Antonio Fasano, et al.
Foilsithe / Cruthaithe: (2011-03-01)

Tunable hybrid hydrogels with multicellular spheroids for modeling desmoplastic pancreatic cancer
de réir: Menekse Ermis, et al.
Foilsithe / Cruthaithe: (2023-07-01)

Monocyte Infiltration and Differentiation in 3D Multicellular Spheroid Cancer Models
de réir: Natasha Helleberg Madsen, et al.
Foilsithe / Cruthaithe: (2021-07-01)

Modelling of complex multicellular systems: tumour-immune cells competition
de réir: Castellano G, et al.
Foilsithe / Cruthaithe: (2009-06-01)

Study of the Chemotactic Response of Multicellular Spheroids in a Microfluidic Device.
de réir: Jose M Ayuso, et al.
Foilsithe / Cruthaithe: (2015-01-01)

In silico analysis of cell cycle synchronisation effects in radiotherapy of tumour spheroids.
de réir: Harald Kempf, et al.
Foilsithe / Cruthaithe: (2013-01-01)

Penetration of Endothelial Cell Coated Multicellular Tumor Spheroids by Iron Oxide Nanoparticles
de réir: Don N. Ho, Nathan Kohler, Aruna Sigdel, Raghu Kalluri, Jeffrey R. Morgan, Chenjie Xu, Shouheng Sun
Foilsithe / Cruthaithe: (2012-01-01)

Structured multicellular intestinal spheroids (SMIS) as a standardized model for infection biology
de réir: Angelina Kraski, et al.
Foilsithe / Cruthaithe: (2024-09-01)

Recent Advances in Multicellular Tumor Spheroid Generation for Drug Screening
de réir: Kwang-Ho Lee, et al.
Foilsithe / Cruthaithe: (2021-11-01)

Linking hypoxia, DNA damage and proliferation in multicellular tumor spheroids
de réir: Stephen Riffle, et al.
Foilsithe / Cruthaithe: (2017-05-01)

Mimicking the immunosuppressive impact of fibroblasts in a 3D multicellular spheroid model
de réir: Melanie Grotz, et al.
Foilsithe / Cruthaithe: (2024-07-01)

Numerical Modelling of Multicellular Spheroid Compression: Viscoelastic Fluid vs. Viscoelastic Solid
de réir: Ruslan Yanbarisov, et al.
Foilsithe / Cruthaithe: (2021-09-01)

Episodic, transient systemic acidosis delays evolution of the malignant phenotype: Possible mechanism for cancer prevention by increased physical activity
de réir: Maini Philip K, et al.
Foilsithe / Cruthaithe: (2010-04-01)