Modelling acidosis and the cell cycle in multicellular tumour spheroids

Modelling acidosis and the cell cycle in multicellular tumour spheroids

A partial differential equation model is developed to understand the effect that nutrient and acidosis have on the distribution of proliferating and quiescent cells and dead cell material (necrotic and apoptotic) within a multicellular tumour spheroid. The rates of cell quiescence and necrosis depen...

Bibliografske podrobnosti
Main Authors:	Tindall, M, Dyson, L, Smallbone, K, Maini, P
Format:	Journal article
Izdano:	Elsevier 2012

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