The Caenorhabditis elegans GATA factor ELT-1 works through the cell proliferation regulator BRO-1 and the Fusogen EFF-1 to maintain the seam stem-like fate.
Seam cells in Caenorhabditis elegans provide a paradigm for the stem cell mode of division, with the ability to both self-renew and produce daughters that differentiate. The transcription factor RNT-1 and its DNA binding partner BRO-1 (homologues of the mammalian cancer-associated stem cell regulato...
Hlavní autoři: | Brabin, C, Appleford, P, Woollard, A |
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Médium: | Journal article |
Jazyk: | English |
Vydáno: |
Public Library of Science
2011
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