CCL19 and CCL21 induce a potent proinflammatory differentiation program in licensed dendritic cells.

CCL19 and CCL21 induce a potent proinflammatory differentiation program in licensed dendritic cells.

Dendritic cells (DCs) are key instigators of adaptive immune responses. Using an alphaviral expression cloning technology, we have identified the chemokine CCL19 as a potent inducer of T cell proliferation in a DC-T cell coculture system. Subsequent studies showed that CCL19 enhanced T cell prolifer...

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Detalhes bibliográficos
Principais autores: Marsland, B, Bättig, P, Bauer, M, Ruedl, C, Lässing, U, Beerli, R, Dietmeier, K, Ivanova, L, Pfister, T, Vogt, L, Nakano, H, Nembrini, C, Saudan, P, Kopf, M, Bachmann, M
Formato: Journal article
Idioma:English
Publicado em: 2005

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