The transcription factor Erg inhibits vascular inflammation by repressing NF-kappaB activation and proinflammatory gene expression in endothelial cells.

The transcription factor Erg inhibits vascular inflammation by repressing NF-kappaB activation and proinflammatory gene expression in endothelial cells.

OBJECTIVE: To test whether ETS-related gene (Erg) inhibits tumor necrosis factor (TNF)-α-dependent endothelial activation and inflammation. METHODS AND RESULTS: Endothelial activation underlies many vascular diseases, including atherosclerosis. Endothelial activation by proinflammatory cytokines dec...

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Bibliographic Details
Main Authors:	Sperone, A, Dryden, N, Birdsey, G, Madden, L, Johns, M, Evans, P, Mason, J, Haskard, DO, Boyle, J, Paleolog, E, Randi, A
Format:	Journal article
Language:	English
Published:	2011

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