Integrin inside-out signaling and the immunological synapse.

Integrin inside-out signaling and the immunological synapse.

Integrins dynamically equilibrate between three conformational states on cell surfaces. A bent conformation has a closed headpiece. Two extended conformations contain either a closed or an open headpiece. Headpiece opening involves hybrid domain swing-out and a 70 Å separation at the integrin knees,...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Springer, T, Dustin, M
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	2012

Eitemau Tebyg

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