Blimp1/Prdm1 governs terminal differentiation of endovascular trophoblast giant cells and defines multipotent progenitors in the developing placenta.
Developmental arrest of Blimp1/Prdm1 mutant embryos at around embryonic day 10.5 (E10.5) has been attributed to placental disturbances. Here we investigate Blimp1/Prdm1 requirements in the trophoblast cell lineage. Loss of function disrupts specification of the invasive spiral artery-associated trop...
Egile Nagusiak: | Mould, A, Morgan, M, Li, L, Bikoff, E, Robertson, E |
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Formatua: | Journal article |
Hizkuntza: | English |
Argitaratua: |
2012
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Antzeko izenburuak
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An expanding job description for Blimp-1/PRDM1.
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