Blimp1/Prdm1 governs terminal differentiation of endovascular trophoblast giant cells and defines multipotent progenitors in the developing placenta.

Blimp1/Prdm1 governs terminal differentiation of endovascular trophoblast giant cells and defines multipotent progenitors in the developing placenta.

Developmental arrest of Blimp1/Prdm1 mutant embryos at around embryonic day 10.5 (E10.5) has been attributed to placental disturbances. Here we investigate Blimp1/Prdm1 requirements in the trophoblast cell lineage. Loss of function disrupts specification of the invasive spiral artery-associated trop...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Mould, A, Morgan, M, Li, L, Bikoff, E, Robertson, E
स्वरूप:	Journal article
भाषा:	English
प्रकाशित:	2012

समान संसाधन

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