Asymmetric synthesis of homochiral Baylis-Hillman products employing (R)-N-methyl-N-alpha-methylbenzyl amide
The conjugate addition of (R)-N-methyl-N-α-methylbenzyl amide to tert-butyl cinnamate followed by an asymmetric aldol reaction and subsequent N-oxidation/Cope elimination affords β-substituted homochiral Baylis-Hillman products in good yield. Copyright (C) 2000 Elsevier Science Ltd.
Hlavní autoři: | Davies, S, Smethurst, C, Smith, A, Smyth, G |
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Médium: | Journal article |
Jazyk: | English |
Vydáno: |
2000
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