The histone deacetylase inhibitor panobinostat as a radiosensitiser in bladder cancer
<p>Muscle invasive bladder cancer (MIBC) has a poor prognosis. Currently, therapy consists of radical radiotherapy or cystectomy with or without chemotherapy. The average age of patients with MIBC is high and older patients are less able to tolerate surgery or chemoradiation due to their impai...
Tác giả chính: | Groselj, B |
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Tác giả khác: | Kiltie, A |
Định dạng: | Luận văn |
Ngôn ngữ: | English |
Được phát hành: |
2014
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Những chủ đề: |
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Radiosensitisation of bladder cancer cells by panobinostat is modulated by Ku80 expression.
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Histone deacetylase inhibitors as radiosensitisers: effects on DNA damage signalling and repair.
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