Centrosome amplification and cancer: A question of sufficiency.
Centrosome amplification is a common feature of many types of cancer, but whether it is a cause or consequence is hotly debated. In this issue of Developmental Cell, Levine et al. (2017) provide strong evidence that centrosome amplification is sufficient to initiate tumorigenesis in a mouse model.
Príomhchruthaitheoirí: | Raff, J, Basto, R |
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Formáid: | Journal article |
Teanga: | English |
Foilsithe / Cruthaithe: |
Elsevier
2017
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Míreanna comhchosúla
Míreanna comhchosúla
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Centrosome amplification can initiate tumorigenesis in flies.
de réir: Basto, R, et al.
Foilsithe / Cruthaithe: (2008) -
Centrosome loss or amplification does not dramatically perturb global gene expression in Drosophila.
de réir: Baumbach, J, et al.
Foilsithe / Cruthaithe: (2012) -
Centrosomes and cancer: lessons from a TACC.
de réir: Raff, J
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Centrosomes: Central no more?
de réir: Raff, J
Foilsithe / Cruthaithe: (2001) -
Centrosome loss or amplification does not dramatically perturb global gene expression in Drosophila
de réir: Janina Baumbach, et al.
Foilsithe / Cruthaithe: (2012-08-01)