Role of the transcription factor sox4 in insulin secretion and impaired glucose tolerance.

Role of the transcription factor sox4 in insulin secretion and impaired glucose tolerance.

OBJECTIVES: To identify, map, clone, and functionally validate a novel mouse model for impaired glucose tolerance and insulin secretion. RESEARCH DESIGN AND METHODS: Haploinsufficiency of the insulin receptor and associated mild insulin resistance has been used to sensitize an N-ethyl-N-nitrosourea...

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Main Authors:	Goldsworthy, M, Hugill, A, Freeman, H, Horner, E, Shimomura, K, Bogani, D, Pieles, G, Mijat, V, Arkell, R, Bhattacharya, S, Ashcroft, F, Cox, R
Format:	Journal article
Language:	English
Published:	2008

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