Breast cancer cells interact with osteoblasts to support osteoclast formation.
Breast cancers commonly cause osteolytic metastases in bone, a process that is dependent upon osteoclast-mediated bone resorption. Recently the osteoclast differentiation factor (ODF), better termed RANKL (receptor activator of NF-kappaB ligand), expressed by osteoblasts has been cloned as well as i...
Main Authors: | , , , , , , |
---|---|
Formato: | Journal article |
Idioma: | English |
Publicado: |
1999
|