Low frequency variants in the exons only encoding isoform A of HNF1A do not contribute to susceptibility to Type 2 diabetes

Background: There is considerable interest in the hypothesis that low frequency, intermediate penetrance variants contribute to the proportion of Type 2 Diabetes (T2D) susceptibility not attributable to the common variants uncovered through genome-wide association approaches. Genes previously implic...

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Hlavní autoři: Jafar-Mohammadi, B, Groves, C, Owen, K, Frayling, T, Hattersley, A, McCarthy, M, Gloyn, A
Médium: Journal article
Jazyk:English
Vydáno: Public Library of Science 2009
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