Inflammatory cues enhance TGFβ activation by distinct subsets of human intestinal dendritic cells via integrin αvβ8

Inflammatory cues enhance TGFβ activation by distinct subsets of human intestinal dendritic cells via integrin αvβ8

Regulation of intestinal T-cell responses is crucial for immune homeostasis and prevention of inflammatory bowel disease (IBD). A vital cytokine in regulating intestinal T cells is transforming growth factor-β (TGFβ), which is secreted by cells as a latent complex that requires activation to functio...

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Những tác giả chính:	Fenton, T, Kelly, A, Shuttleworth, E, Smedley, C, Atakilit, A, Powrie, F, Campbell, S, Nishimura, S, Sheppard, D, Levison, S, Worthington, J, Lehtinen, M, Travis, M
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	Springer Nature 2016

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