Inflammatory cues enhance TGFβ activation by distinct subsets of human intestinal dendritic cells via integrin αvβ8

Regulation of intestinal T-cell responses is crucial for immune homeostasis and prevention of inflammatory bowel disease (IBD). A vital cytokine in regulating intestinal T cells is transforming growth factor-β (TGFβ), which is secreted by cells as a latent complex that requires activation to functio...

詳細記述

書誌詳細
主要な著者: Fenton, T, Kelly, A, Shuttleworth, E, Smedley, C, Atakilit, A, Powrie, F, Campbell, S, Nishimura, S, Sheppard, D, Levison, S, Worthington, J, Lehtinen, M, Travis, M
フォーマット: Journal article
言語:English
出版事項: Springer Nature 2016