Inflammatory cues enhance TGFβ activation by distinct subsets of human intestinal dendritic cells via integrin αvβ8

Regulation of intestinal T-cell responses is crucial for immune homeostasis and prevention of inflammatory bowel disease (IBD). A vital cytokine in regulating intestinal T cells is transforming growth factor-β (TGFβ), which is secreted by cells as a latent complex that requires activation to functio...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Fenton, T, Kelly, A, Shuttleworth, E, Smedley, C, Atakilit, A, Powrie, F, Campbell, S, Nishimura, S, Sheppard, D, Levison, S, Worthington, J, Lehtinen, M, Travis, M
Формат: Journal article
Хэл сонгох:English
Хэвлэсэн: Springer Nature 2016