Ghrelin exerts a proliferative effect on a rat pituitary somatotroph cell line via the mitogen-activated protein kinase pathway.

Ghrelin exerts a proliferative effect on a rat pituitary somatotroph cell line via the mitogen-activated protein kinase pathway.

OBJECTIVES: Ghrelin is a brain-gut peptide with GH-releasing and appetite-inducing activities and a widespread tissue distribution. Ghrelin is the endogenous ligand of the GH secretagogue receptor type 1a (GHS-R1a), and both ghrelin and the GHS-R1a are expressed in the pituitary. There are conflict...

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Bibliografiske detaljer
Main Authors:	Nanzer, A, Khalaf, S, Mozid, A, Fowkes, R, Patel, M, Burrin, J, Grossman, AB, Korbonits, M
Format:	Journal article
Sprog:	English
Udgivet:	2004

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