Inflammatory regulation of glucocorticoid metabolism in mesenchymal stromal cells.

Inflammatory regulation of glucocorticoid metabolism in mesenchymal stromal cells.

OBJECTIVE: Tissue glucocorticoid (GC) levels are regulated by the GC-activating enzyme 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1). This enzyme is expressed in cells and tissues arising from mesenchymal stromal cells. Proinflammatory cytokines dramatically increase expression of 11β-HSD1 in s...

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Manylion Llyfryddiaeth
Prif Awduron: Ahasan, M, Hardy, R, Jones, C, Kaur, K, Nanus, D, Juarez, M, Morgan, SA, Hassan-Smith, Z, Bénézech, C, Caamaño, J, Hewison, M, Lavery, G, Rabbitt, E, Clark, A, Filer, A, Buckley, C, Raza, K, Stewart, P, Cooper, MS
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 2012

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