Similarities and differences between human and murine TNF promoters in their response to lipopolysaccharide.

Transcription of the TNF gene is rapidly and transiently induced by LPS in cells of monocyte/macrophage lineage. Previous data suggested that multiple NF-kappaB/Rel binding sites play a role in the transcriptional response to LPS of the murine gene. However, the relevance of homologous sites in the...

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Hlavní autoři: Kuprash, D, Udalova, I, Turetskaya, R, Kwiatkowski, D, Rice, N, Nedospasov, SA
Médium: Journal article
Jazyk:English
Vydáno: 1999