Functional and inhibition studies on 2-oxoglutarate-dependent oxygenases

Functional and inhibition studies on 2-oxoglutarate-dependent oxygenases

<p>This thesis explores roles of 2-oxoglutarate-dependent (2OG) oxygenases as interfaces that modulate steps in the flow of genetic information in cells in response to oxygen availability. Chapter 1 introduces mechanistic, biochemical and physiological aspects of major subfamilies of 2OG oxyge...

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Bibliografiske detaljer
Hovedforfatter:	Thalhammer, A
Andre forfattere:	Schofield, C
Format:	Thesis
Sprog:	English
Udgivet:	2012
Fag:	Tumours Oncology Protein chemistry High-Throughput Screening Antibiotics Computer aided molecular and material design Organic synthesis Enzymes Biophysical chemistry DNA damage signalling Biochemistry Organic chemistry

Lignende værker

Kinetic and mechanistic studies of oxygen sensing Fe(II)/2-oxoglutarate dependent oxygenases
af: Tarhonskaya, H
Udgivet: (2014)

Interplay between 2-oxoglutarate oxygenases and cancer: studies on the aspartyl/asparaginyl-beta-hydroxylase
af: Pfeffer, I
Udgivet: (2014)

NMR studies on 2-oxoglutarate oxygenases
af: Leung, IKH
Udgivet: (2013)

Mechanistic studies on 2-oxoglutarate dependent oxygenases
af: Szollossi, A
Udgivet: (2012)

Isoenzyme specific PFK-2/FBPas-2 inhibition as an anti-cancer strategy
af: Williams, J
Udgivet: (2013)

Studies on ribosomal oxygenases
af: Sekirnik, R
Udgivet: (2014)

Dynamic combinatorial mass spectrometry for 2-oxoglutarate oxygenase inhibition
af: Demetriades, M
Udgivet: (2013)

A glycopore for bacterial sensing
af: Shanley, SJ
Udgivet: (2009)

Molecular characterisation of bacterial proteins that interact with sulfur or nitrogen compounds
af: Grabarczyk, D, et al.
Udgivet: (2014)

Chemical and biological studies on human oxygenases
af: Thinnes, C, et al.
Udgivet: (2014)

Amyloid-beta–copper interaction studied by simultaneous nitrogen K and copper L2,3-edge soft X-ray absorption spectroscopy
af: Jinghui Luo, et al.
Udgivet: (2021-12-01)

Computational studies of ligand-water mediated interactions in ionotropic glutamate receptors
af: Sahai, M
Udgivet: (2011)

A laboratory manual for general, organic, and biochemistry /
af: 530999 Henrickson, Charles H., et al.
Udgivet: (2011)

General, organic and biological chemistry [electronic resource] /
af: 260120 Arnold, Melvin T.
Udgivet: (2001)

General, organic, and biological chemistry /
af: 388406 Stoker, H. Stephen
Udgivet: (2010)

Fundamentals of organic and biological chemistry /
af: 265039 McMurry, John, et al.
Udgivet: (1994)

Exercises in general, organic, and biological chemistry /
af: 238301 Langsjoen, Arne N.
Udgivet: (1973)

Essentials of general, organic & biological chemistry /
af: 260120 Arnold, Melvin T.
Udgivet: (2001)

General, organic, and biological chemistry /
af: 388406 Stoker, H. Stephen (Howard Stephen), 1939-
Udgivet: (2007)

Structure and function of bacterial proteins secreted by the type three secretion and twin arginine translocation pathways
af: Lillington, J, et al.
Udgivet: (2011)

Engineered α-hemolysin pores with chemically and genetically-fused functional proteins
af: Mantri, S
Udgivet: (2013)

Engineered α-hemolysin pores with chemically and genetically-fused functional proteins
af: Mantri, S
Udgivet: (2013)

Molecular mechanisms of drug transport through peptide transporters
af: Lichtinger, SM
Udgivet: (2024)

Probing sulfatide-tissue lectin recognition with functionalized glycodendrimersomes
af: Paul V. Murphy, et al.
Udgivet: (2021-01-01)

Chemical tools for the study of epigenetic mechanisms
af: Lercher, L
Udgivet: (2014)

Probes for bacterial ion channels
af: Swallow, I
Udgivet: (2014)

The synthesis and biological evaluation of novel N-acetylhexosaminidase inhibitors
af: Crabtree, E, et al.
Udgivet: (2011)

Synthesis of Mycobacterium tuberculosis ATP synthase inhibitors
af: Pattarakiat, Seankongsuk
Udgivet: (2022)

The synthesis of branched sugars and iminosugars
af: Parry, LL
Udgivet: (2011)

Mechanism of SigR inhibition by the anti-sigma factor RsrA from Streptomyces coelicolor
af: Francis, M, et al.
Udgivet: (2015)

Development of clinical biomarkers of DNA double strand breaks for cancer care
af: Shah, K
Udgivet: (2012)

Essentials of organic chemistry : for students of pharmacy, medicinal chemistry and biological chemistry /
af: 465929 Dewick, Paul M.
Udgivet: (2006)

Bio-organic chemistry /
af: Chopra, Harish K., author, et al.
Udgivet: (♭201)

Synthesis, single crystal analysis, biological and docking evaluation of tetrazole derivatives
af: Hamid Aziz, et al.
Udgivet: (2018-09-01)

Single molecule studies of a voltage-gated potassium channel
af: Angué, L
Udgivet: (2013)

Proteomics-aided search for extracellular matrix signatures of colorectal hepatic metastases ex vivo
af: Yuzhalin, A
Udgivet: (2014)

Bioelectrochemistry by fluorescent cyclic voltammetry
af: Mizzon, G
Udgivet: (2012)

Energy transfer and trapping in photosystem I with and without chlorophyll-f
af: Ivo H.M. van Stokkum, et al.
Udgivet: (2023-09-01)

The role of LATS1 in DNA damage signalling
af: Latusek, R
Udgivet: (2012)

Recent advances in organic chemsitry/
af: 174975 Stewart, Alfred Walter
Udgivet: (1948)