Up-regulation of the lymphatic marker podoplanin, a mucin-type transmembrane glycoprotein, in human squamous cell carcinomas and germ cell tumors.
The mucin-type glycoprotein podoplanin is specifically expressed by lymphatic but not blood vascular endothelial cells in culture and in tumor-associated lymphangiogenesis, and podoplanin deficiency results in congenital lymphedema and impaired lymphatic vascular patterning. However, research into t...
Main Authors: | Schacht, V, Dadras, S, Johnson, L, Jackson, D, Hong, Y, Detmar, M |
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Format: | Journal article |
Language: | English |
Published: |
2005
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