Time-dependent pharmacokinetics and drug metabolism of atovaquone plus proguanil (Malarone) when taken as chemoprophylaxis.

OBJECTIVE: To determine the pharmacokinetic profiles of atovaquone (ATO), proguanil (PROG) and its active metabolite cycloguanil (CYCLO) with respect to possible accumulation and kinetic interaction upon repeated dosing with Malarone. METHODS: Thirteen healthy volunteers first received a single dos...

Celý popis

Podrobná bibliografie
Hlavní autoři:	Thapar, M, Ashton, M, Lindegårdh, N, Bergqvist, Y, Nivelius, S, Johansson, I, Björkman, A
Médium:	Journal article
Jazyk:	English
Vydáno:	2002

Time-dependent pharmacokinetics and drug metabolism of atovaquone plus proguanil (malarone) when taken as chemoprophylaxis Autor Mita, T, Ashton, M, Lindegardh, N, Bergqvist, Y, Nivelius, S, Johansson, I, Bjorkman, A

Vydáno 2003

Conference item

Time-dependent pharmacokinetics and drug metabolism of atovaquone plus proguanil (Malarone) when taken as chemoprophylaxis Autor Mita, T, Ashton, M, Lindegardh, N, Bergqvist, Y, Nivelius, S, Johansson, I, Bjorkman, A

Vydáno 2003

Conference item

Time-dependent pharmacokinetics and drug metabolism of atovaquone plus proguanil (Malarone) when taken as chemoprophylaxis.

Time-dependent pharmacokinetics and drug metabolism of atovaquone plus proguanil (malarone) when taken as chemoprophylaxis Autor Mita, T, Ashton, M, Lindegardh, N, Bergqvist, Y, Nivelius, S, Johansson, I, Bjorkman, A

Time-dependent pharmacokinetics and drug metabolism of atovaquone plus proguanil (Malarone) when taken as chemoprophylaxis Autor Mita, T, Ashton, M, Lindegardh, N, Bergqvist, Y, Nivelius, S, Johansson, I, Bjorkman, A

Podobné jednotky