G-CSF rescues tumor growth and neo-angiogenesis during liver metastasis under host angiopoietin-2 deficiency

G-CSF rescues tumor growth and neo-angiogenesis during liver metastasis under host angiopoietin-2 deficiency

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Suppression of neo-angiogenesis is a clinically used anti-tumor strategy with new targets such as angiopoietin-2 (Ang2) being proposed. However, the functions of Ang2 in vascular remodeling, inflammation and tumor growth are not consistent. We examined effect of depletion of host Ang2 on liver colon...

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Détails bibliographiques
Auteurs principaux:	Im, J, Tapmeier, T, Balathasan, L, Gal, A, Yameen, S, Hill, S, Smart, S, Noterdaeme, O, Kelly, M, Brady, M, Fu, W, Kruse, K, Bernhard, E, Augustin, H, Muschel, R
Format:	Journal article
Langue:	English
Publié:	2013

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