An ankylosing spondylitis-associated genetic variant in the IL23R-IL12RB2 intergenic region modulates enhancer activity and is associated with increased Th1-cell differentiation
<p><strong>Objectives</strong> To explore the functional basis for the association between ankylosing spondylitis (AS) and single-nucleotide polymorphisms (SNPs) in the IL23R-IL12RB2 intergenic region.</p> <p><strong>Methods</strong> We performed conditiona...
Príomhchruthaitheoirí: | Roberts, AR, Vecellio, M, Chen, L, Ridley, A, Cortes, A, Knight, JC, Bowness, P, Cohen, CJ, Wordsworth, BP |
---|---|
Formáid: | Journal article |
Teanga: | English |
Foilsithe / Cruthaithe: |
BMJ Publishing Group
2016
|
Míreanna comhchosúla
Míreanna comhchosúla
-
ANKYLOSING SPONDYLITIS-ASSOCIATED SNPS AT THE IL23R-IL12RB2 INTERGENIC REGION ARE FUNCTIONALLY IMPORTANT
de réir: Roberts, A, et al.
Foilsithe / Cruthaithe: (2014) -
OP0231 Differential transcription factor binding could explain the genetic association of ankylosing spondylitis with polymorphisms in the IL23R-IL12RB2 intergenic region
de réir: Roberts, AR, et al.
Foilsithe / Cruthaithe: (2016) -
Investigation of a possible extended risk haplotype in the IL23R region associated with ankylosing spondylitis
de réir: Roberts, A, et al.
Foilsithe / Cruthaithe: (2017) -
EPIGENETIC REGULATION OF THE IL-23R LOCUS IN ANKYLOSING SPONDYLITIS
de réir: Cohen, C, et al.
Foilsithe / Cruthaithe: (2013) -
Perspectives on the genetic associations of ankylosing spondylitis
de réir: Wordsworth, BP, et al.
Foilsithe / Cruthaithe: (2021)