Human Pcf11 enhances degradation of RNA polymerase II-associated nascent RNA and transcriptional termination.
The poly(A) (pA) signal possesses a dual function in 3' end processing of pre-mRNA and in transcriptional termination of RNA polymerase II (Pol II) for most eukaryotic protein-coding genes. A key protein factor in yeast and Drosophila Pol II transcriptional termination is the 3'-end proces...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2008
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