Human Pcf11 enhances degradation of RNA polymerase II-associated nascent RNA and transcriptional termination.

The poly(A) (pA) signal possesses a dual function in 3' end processing of pre-mRNA and in transcriptional termination of RNA polymerase II (Pol II) for most eukaryotic protein-coding genes. A key protein factor in yeast and Drosophila Pol II transcriptional termination is the 3'-end proces...

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Autors principals: West, S, Proudfoot, N
Format: Journal article
Idioma:English
Publicat: 2008