Human Pcf11 enhances degradation of RNA polymerase II-associated nascent RNA and transcriptional termination.

The poly(A) (pA) signal possesses a dual function in 3' end processing of pre-mRNA and in transcriptional termination of RNA polymerase II (Pol II) for most eukaryotic protein-coding genes. A key protein factor in yeast and Drosophila Pol II transcriptional termination is the 3'-end proces...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: West, S, Proudfoot, N
Aineistotyyppi: Journal article
Kieli:English
Julkaistu: 2008