Effect of exercise on depression severity in older people: systematic review and meta-analysis of randomised controlled trials.
BACKGROUND: The prevalence of depression in older people is high, treatment is inadequate, it creates a substantial burden and is a public health priority for which exercise has been proposed as a therapeutic strategy. AIMS: To estimate the effect of exercise on depressive symptoms among older peop...
| Main Authors: | , , , , |
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| Format: | Journal article |
| Language: | English |
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2012
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| _version_ | 1826269467539144704 |
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| author | Bridle, C Spanjers, K Patel, S Atherton, N Lamb, S |
| author_facet | Bridle, C Spanjers, K Patel, S Atherton, N Lamb, S |
| author_sort | Bridle, C |
| collection | OXFORD |
| description | BACKGROUND: The prevalence of depression in older people is high, treatment is inadequate, it creates a substantial burden and is a public health priority for which exercise has been proposed as a therapeutic strategy. AIMS: To estimate the effect of exercise on depressive symptoms among older people, and assess whether treatment effect varies depending on the depression criteria used to determine participant eligibility. METHOD: Systematic review and meta-analysis of randomised controlled trials of exercise for depression in older people. RESULTS: Nine trials met the inclusion criteria and seven were meta-analysed. Exercise was associated with significantly lower depression severity (standardised mean difference (SMD) = -0.34, 95% CI -0.52 to -0.17), irrespective of whether participant eligibility was determined by clinical diagnosis (SMD = -0.38, 95% CI -0.67 to -0.10) or symptom checklist (SMD = -0.34, 95% CI -0.62 to -0.06). Results remained significant in sensitivity analyses. CONCLUSIONS: Our findings suggest that, for older people who present with clinically meaningful symptoms of depression, prescribing structured exercise tailored to individual ability will reduce depression severity. |
| first_indexed | 2024-03-06T21:25:30Z |
| format | Journal article |
| id | oxford-uuid:42f6e2d1-afd7-460c-8066-f3c31d20b46d |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T21:25:30Z |
| publishDate | 2012 |
| record_format | dspace |
| spelling | oxford-uuid:42f6e2d1-afd7-460c-8066-f3c31d20b46d2022-03-26T14:52:28ZEffect of exercise on depression severity in older people: systematic review and meta-analysis of randomised controlled trials.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:42f6e2d1-afd7-460c-8066-f3c31d20b46dEnglishSymplectic Elements at Oxford2012Bridle, CSpanjers, KPatel, SAtherton, NLamb, S BACKGROUND: The prevalence of depression in older people is high, treatment is inadequate, it creates a substantial burden and is a public health priority for which exercise has been proposed as a therapeutic strategy. AIMS: To estimate the effect of exercise on depressive symptoms among older people, and assess whether treatment effect varies depending on the depression criteria used to determine participant eligibility. METHOD: Systematic review and meta-analysis of randomised controlled trials of exercise for depression in older people. RESULTS: Nine trials met the inclusion criteria and seven were meta-analysed. Exercise was associated with significantly lower depression severity (standardised mean difference (SMD) = -0.34, 95% CI -0.52 to -0.17), irrespective of whether participant eligibility was determined by clinical diagnosis (SMD = -0.38, 95% CI -0.67 to -0.10) or symptom checklist (SMD = -0.34, 95% CI -0.62 to -0.06). Results remained significant in sensitivity analyses. CONCLUSIONS: Our findings suggest that, for older people who present with clinically meaningful symptoms of depression, prescribing structured exercise tailored to individual ability will reduce depression severity. |
| spellingShingle | Bridle, C Spanjers, K Patel, S Atherton, N Lamb, S Effect of exercise on depression severity in older people: systematic review and meta-analysis of randomised controlled trials. |
| title | Effect of exercise on depression severity in older people: systematic review and meta-analysis of randomised controlled trials. |
| title_full | Effect of exercise on depression severity in older people: systematic review and meta-analysis of randomised controlled trials. |
| title_fullStr | Effect of exercise on depression severity in older people: systematic review and meta-analysis of randomised controlled trials. |
| title_full_unstemmed | Effect of exercise on depression severity in older people: systematic review and meta-analysis of randomised controlled trials. |
| title_short | Effect of exercise on depression severity in older people: systematic review and meta-analysis of randomised controlled trials. |
| title_sort | effect of exercise on depression severity in older people systematic review and meta analysis of randomised controlled trials |
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