Swiprosin-1/EFhd2 controls B cell receptor signaling through the assembly of the B cell receptor, Syk, and phospholipase C gamma2 in membrane rafts.

Swiprosin-1/EFhd2 controls B cell receptor signaling through the assembly of the B cell receptor, Syk, and phospholipase C gamma2 in membrane rafts.

Compartmentalization of the BCR in membrane rafts is important for its signaling capacity. Swiprosin-1/EFhd2 (Swip-1) is an EF-hand and coiled-coil-containing adaptor protein with predicted Src homology 3 (SH3) binding sites that we identified in membrane rafts. We showed previously that Swip-1 ampl...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Kroczek, C, Lang, C, Brachs, S, Grohmann, M, Dütting, S, Schweizer, A, Nitschke, L, Feller, S, Jäck, H, Mielenz, D
Формат:	Journal article
Хэл сонгох:	English
Хэвлэсэн:	2010

Ижил төстэй зүйлс

Swiprosin 1 – regulator of proximal BCR signaling
-н: Mielenz D, зэрэг
Хэвлэсэн: (2009-02-01)

B Cell Speed and B-FDC Contacts in Germinal Centers Determine Plasma Cell Output via Swiprosin-1/EFhd2
-н: Dorothea Reimer, зэрэг
Хэвлэсэн: (2020-08-01)

The Ca2+ sensor protein swiprosin-1/EFhd2 is present in neurites and involved in kinesin-mediated transport in neurons.
-н: Pavitra Purohit, зэрэг
Хэвлэсэн: (2014-01-01)

Structural and Biochemical Characterization of EFhd1/Swiprosin-2, an Actin-Binding Protein in Mitochondria
-н: Sang A. Mun, зэрэг
Хэвлэсэн: (2021-01-01)

Role of Syk in B-cell development and antigen-receptor signaling.
-н: Cornall, R, зэрэг
Хэвлэсэн: (2000)

B cell activation involves nanoscale receptor reorganizations and inside-out signaling by Syk
-н: Kathrin Kläsener, зэрэг
Хэвлэсэн: (2014-06-01)

Structural and biochemical insights into Zn2+-bound EF-hand proteins, EFhd1 and EFhd2
-н: Sang A Mun, зэрэг
Хэвлэсэн: (2023-03-01)

Monovalent and Multivalent Ligation of the B Cell Receptor Exhibit Differential Dependence upon Syk and Src Family Kinases
-н: Mukherjee, Sayak, зэрэг
Хэвлэсэн: (2014)

Dual BTK/SYK inhibition with CG-806 (luxeptinib) disrupts B-cell receptor and Bcl-2 signaling networks in mantle cell lymphoma
-н: Elana Thieme, зэрэг
Хэвлэсэн: (2022-03-01)

SYK inhibition thwarts the BAFF - B-cell receptor crosstalk and thereby antagonizes Mcl-1 in chronic lymphocytic leukemia
-н: Cody Paiva, зэрэг
Хэвлэсэн: (2017-11-01)

Are rafts involved in T-cell receptor signalling? Introduction to the Talking Point on the involvement of lipid rafts in T-cell activation.
-н: de Wet, B, зэрэг
Хэвлэсэн: (2008)

EFhd2 co-aggregates with monomeric and filamentous tau in vitro
-н: Ahlam S. Soliman, зэрэг
Хэвлэсэн: (2024-05-01)

EFHD2 suppresses intestinal inflammation by blocking intestinal epithelial cell TNFR1 internalization and cell death
-н: Jiacheng Wu, зэрэг
Хэвлэсэн: (2024-02-01)

Human dendritic cell maturation induced by amorphous silica nanoparticles is Syk-dependent and triggered by lipid raft aggregation
-н: Éléonore Guillet, зэрэг
Хэвлэсэн: (2023-04-01)

Mercury alters endogenous phosphorylation profiles of SYK in murine B cells
-н: Joseph A. Caruso, зэрэг
Хэвлэсэн: (2017-07-01)

Expression of Phospholipase A2 Receptor in Pediatric Hepatitis B Virus-Related Membranous Nephropathy
-н: Sung-Eun Choi, зэрэг
Хэвлэсэн: (2020-04-01)

Lipid raft domains and protein networks in T-cell receptor signal transduction.
-н: Harder, T
Хэвлэсэн: (2004)

Lipid raft domains and protein networks in T-cell receptor signal transduction
-н: Harder, T
Хэвлэсэн: (2004)

Lipid Rafts Interaction of the ARID3A Transcription Factor with EZRIN and G-Actin Regulates B-Cell Receptor Signaling
-н: Christian Schmidt, зэрэг
Хэвлэсэн: (2021-03-01)

PCSK9 stimulates Syk, PKCδ, and NF-κB, leading to atherosclerosis progression independently of LDL receptor
-н: Dasom Shin, зэрэг
Хэвлэсэн: (2024-03-01)

Modulation of BCR Signaling by the Induced Dimerization of Receptor-Associated SYK
-н: Mark L. Westbroek, зэрэг
Хэвлэсэн: (2017-12-01)

Entry of Francisella tularensis into Murine B Cells: The Role of B Cell Receptors and Complement Receptors.
-н: Lenka Plzakova, зэрэг
Хэвлэсэн: (2015-01-01)

T-cell receptor and B-cell receptor repertoires profiling in pleural tuberculosis
-н: Fengjiao Du, зэрэг
Хэвлэсэн: (2024-11-01)

Erythropoietin receptor signaling is membrane raft dependent.
-н: Kathy L McGraw, зэрэг
Хэвлэсэн: (2012-01-01)

<i>Stephania tetrandra</i> and Its Active Compound Coclaurine Sensitize NSCLC Cells to Cisplatin through EFHD2 Inhibition
-н: Shu-Yu Hu, зэрэг
Хэвлэсэн: (2024-10-01)

The guanine-nucleotide exchange factor Vav is a crucial regulator of B cell receptor activation and B cell responses to nonrepetitive antigens.
-н: Bachmann, M, зэрэг
Хэвлэсэн: (1999)

Regulation of B cell functions by the sialic acid-binding receptors Siglec-G and CD22
-н: Julia eJellusova, зэрэг
Хэвлэсэн: (2012-01-01)

Induction of lysosomal phospholipase A2 through the retinoid X receptor in THP-1 cells
-н: Akira Abe, зэрэг
Хэвлэсэн: (2004-04-01)

Tau’s Three-Repeat Domain and EFhd2 Co-incubation Leads to Increased Thioflavin Signal
-н: Irving E. Vega, зэрэг
Хэвлэсэн: (2018-12-01)

HSL-knockout mouse testis exhibits class B scavenger receptor upregulation and disrupted lipid raft microdomains[S]
-н: María Emilia Casado, зэрэг
Хэвлэсэн: (2012-12-01)

Phase I study of the Syk inhibitor sovleplenib in relapsed or refractory mature B-cell tumors
-н: Yuqin Song, зэрэг
Хэвлэсэн: (2024-01-01)

EFHD2 contributes to non-small cell lung cancer cisplatin resistance by the activation of NOX4-ROS-ABCC1 axis
-н: Chi-Chen Fan, зэрэг
Хэвлэсэн: (2020-07-01)

Anti-phospholipase A2 receptor antibodies in membranous nephropathy
-н: Sangho Lee
Хэвлэсэн: (2018-09-01)

The shape of the lymphocyte receptor repertoire: lessons from the B cell receptor
-н: Katherine J. L. Jackson, зэрэг
Хэвлэсэн: (2013-09-01)

EFHD1 expression is correlated with tumor-infiltrating neutrophils and predicts prognosis in gastric cancer
-н: Bin Zhao, зэрэг
Хэвлэсэн: (2023-10-01)

Aberrant methylation of the M-type phospholipase A<sub>2</sub> receptor gene in leukemic cells
-н: Menschikowski Mario, зэрэг
Хэвлэсэн: (2012-12-01)

Phospholipase D4 as a signature of toll-like receptor 7 or 9 signaling is expressed on blastic T-bet + B cells in systemic lupus erythematosus
-н: Ken Yasaka, зэрэг
Хэвлэсэн: (2023-10-01)

Characterisation of the mechanism of B-cell receptor triggering
-н: Wilcock, M
Хэвлэсэн: (2018)

Hypercholesterolemia Correlates With Glomerular Phospholipase A2 Receptor Deposit and Serum Anti-Phospholipase A2 Receptor Antibody and Predicts Proteinuria Outcome in Idiopathic Membranous Nephropathy
-н: Lei Dong, зэрэг
Хэвлэсэн: (2022-06-01)

On thermalization in the SYK and supersymmetric SYK models
-н: Nicholas Hunter-Jones, зэрэг
Хэвлэсэн: (2018-02-01)