HLA B27 in health and disease: a double-edged sword?
The strong association of the HLA class 1 allele HLA B27 with ankylosing spondylitis (AS) has been recognized for over 25 yr, however the pathogenic mechanism linking HLA B27 with AS and other spondyloarthropathies remains a mystery. We now know that the principal natural function of HLA B27 is an i...
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| 格式: | Journal article |
| 語言: | English |
| 出版: |
2002
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