CYP3A variation, premenopausal estrone levels, and breast cancer risk.

CYP3A variation, premenopausal estrone levels, and breast cancer risk.

BACKGROUND: Epidemiological studies have provided strong evidence for a role of endogenous sex steroids in the etiology of breast cancer. Our aim was to identify common variants in genes involved in sex steroid synthesis or metabolism that are associated with hormone levels and the risk of breast ca...

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Hlavní autoři: Johnson, N, Walker, K, Gibson, L, Orr, N, Folkerd, E, Haynes, B, Palles, C, Coupland, B, Schoemaker, M, Jones, M, Broderick, P, Sawyer, E, Kerin, M, Tomlinson, I, Zvelebil, M, Chilcott-Burns, S, Tomczyk, K, Simpson, G, Williamson, J, Hillier, S, Ross, G, Houlston, R, Swerdlow, A, Ashworth, A, Dowsett, M
Médium: Journal article
Jazyk:English
Vydáno: 2012

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