Fluorine-directed diastereoselective iodocyclizations.
(Chemical Equation Presented) An inside job: β-Fluorinated lactones and tetrahydrofurans are synthesized by iodocyclization of various allylic fluorides. The fluorine substituent acts as a highly efficient syn-stereodirecting group for the ring closure. The experimental results combined with theoret...
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Bibliographic Details
| Main Authors: |
Tredwell, M,
Luft, J,
Schuler, M,
Tenza, K,
Houk, K,
Gouverneur, V |
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| Format: | Journal article
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| Language: | English |
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| Published: |
2008
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