Heterologous amyloid seeding: revisiting the role of acetylcholinesterase in Alzheimer's disease
Neurodegenerative diseases associated with abnormal protein folding and ordered aggregation require an initial trigger which may be infectious, inherited, post-inflammatory or ideopathic. Proteolytic cleavage to generate vulnerable precursors, such as amyloid-β peptide (Aβ) production via β and γ se...
| Main Authors: | , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Public Library of Science
2007
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| Subjects: |