Nuclear-mitochondrial DNA segments resemble paternally inherited mitochondrial DNA in humans

Several strands of evidence question the dogma that human mitochondrial DNA (mtDNA) is inherited exclusively down the maternal line, most recently in three families where several individuals harbored a 'heteroplasmic haplotype' consistent with biparental transmission. Here we report a simi...

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Hlavní autoři: Wei, W, Pagnamenta, AT, Gleadall, N, Sanchis-Juan, A, Stephens, J, Broxholme, J, Tuna, S, Odhams, CA, Genomics England Research Consortium, NIHR BioResource, Fratter, C, Turro, E, Caulfield, MJ, Taylor, JC, Rahman, S, Chinnery, PF
Médium: Journal article
Jazyk:English
Vydáno: Springer Nature 2020