Nutrient Sensing via mTOR in T Cells Maintains a Tolerogenic Microenvironment.

We have proposed that tolerance can be maintained through the induction, by Treg cells, of a tolerogenic microenvironment within tolerated tissues that inhibits effector cell activity but which supports the generation of further Treg cells by "infectious tolerance." Two important component...

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Bibliographic Details
Main Authors: Howie, D, Waldmann, H, Cobbold, S
Format: Journal article
Language:English
Published: 2014