Glycosphingolipid depletion in PC12 cells using iminosugars protects neuronal membranes from anti-ganglioside antibody mediated injury.

Autoimmune neuropathies are frequently associated with pathogenic anti-ganglioside antibodies targeting ganglioside-rich neuronal and glial membranes. The extent of injury is determined by the concentration of membrane ganglioside and thus reduction might be expected to attenuate disease. In this st...

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Opis bibliograficzny
Główni autorzy: Townson, K, Speak, A, Greenshields, K, Goodyear, C, Willison, H, Platt, F
Format: Journal article
Język:English
Wydane: 2008

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