Genetic interactions with sex make a relatively small contribution to the heritability of complex traits in mice

The extent to which sex-specific genetic effects contribute to phenotypic variation is largely unknown. We applied a novel Bayesian method, sparse partitioning, to detect gene by sex (GxS) and gene by gene (GxG) quantitative loci (QTLs) in 1,900 outbred heterogeneous stock mice. In an analysis of 55...

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Bibliographic Details
Main Authors: Krohn, J, Speed, D, Palme, R, Touma, C, Mott, R, Flint, J
Format: Journal article
Language:English
Published: Public Library of Science 2014

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