Enantioconvergent alkylation of ketones with racemic secondary alcohols via hydrogen borrowing catalysis

Enantioconvergent alkylation of ketones with racemic secondary alcohols via hydrogen borrowing catalysis

An enantioconvergent method for the alkylation of o-disubstituted aryl ketones with racemic secondary alcohols is described. This process is mediated by a commercially available iridium catalyst and proceeds via hydrogen borrowing catalysis. The highly enantioenriched β-substituted ketone products w...

书目详细资料
Main Authors:	Cheang, DMJ, Armstrong, RJ, Akhtar, WM, Donohoe, TJ
格式:	Journal article
语言:	English
出版:	Royal Society of Chemistry 2020

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