Enantioconvergent alkylation of ketones with racemic secondary alcohols via hydrogen borrowing catalysis
An enantioconvergent method for the alkylation of o-disubstituted aryl ketones with racemic secondary alcohols is described. This process is mediated by a commercially available iridium catalyst and proceeds via hydrogen borrowing catalysis. The highly enantioenriched β-substituted ketone products w...
| Hauptverfasser: | , , , |
|---|---|
| Format: | Journal article |
| Sprache: | English |
| Veröffentlicht: |
Royal Society of Chemistry
2020
|