Auger electron radionuclide therapy utilising F3 peptide to target the nucleolus
<p>F3 is a 31 amino acid peptide that possesses tumour homing capability and binds to nucleolin (NCL) expressed on the cell surface of malignant cells. Exposure of osteosarcoma (U2OS) cells to F3 peptide was found to shift the distribution of NCL and nucleophosmin (NPM) from the nucleolus to t...
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| Format: | Thesis |
| Language: | English |
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2015
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