Allele-specific repression of lymphotoxin-alpha by activated B cell factor-1.

Genetic variation at the human LTA locus, encoding lymphotoxin-alpha, is associated with susceptibility to myocardial infarction, asthma and other diseases. By detailed haplotypic analysis of the locus, we identified a single-nucleotide polymorphism (SNP) at LTA+80 as a main predictor of LTA protein...

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Bibliografske podrobnosti
Main Authors: Knight, J, Keating, B, Kwiatkowski, D
Format: Journal article
Jezik:English
Izdano: 2004