Correlation of tolerogenicity of a viral antigen with its immunogenicity.

Correlation of tolerogenicity of a viral antigen with its immunogenicity.

Induction of B cell tolerance or activation was analyzed with vesicular stomatitis virus (VSV) glycoprotein (G) expressed as a neo-self Ag. A membrane form of VSV-G expressed in all tissues, including the bone marrow, induced unresponsiveness at both the Th and B cell level, whereas a soluble form o...

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Bibliographic Details
Main Authors:	Bachmann, M, Fehr, T, Freer, G, Hengartner, H, Zinkernagel, R
Format:	Journal article
Language:	English
Published:	1997

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