Risk factors for adenocarcinoma and squamous cell carcinoma of the cervix in women aged 20-44 years: the UK National Case-Control Study of Cervical Cancer.
We report results on risk factors for invasive squamous cell and adenocarcinomas of the cervix in women aged 20-44 years from the UK National Case-Control Study of Cervical Cancer, including 180 women with adenocarcinoma, 391 women with squamous cell carcinoma and 923 population controls. The risk o...
| Main Authors: | , , , , , , , , , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
2003
|
| _version_ | 1797065409415872512 |
|---|---|
| author | Green, J Berrington de Gonzalez, A Sweetland, S Beral, V Chilvers, C Crossley, B Deacon, J Hermon, C Jha, P Mant, D Peto, J Pike, M Vessey, M |
| author_facet | Green, J Berrington de Gonzalez, A Sweetland, S Beral, V Chilvers, C Crossley, B Deacon, J Hermon, C Jha, P Mant, D Peto, J Pike, M Vessey, M |
| author_sort | Green, J |
| collection | OXFORD |
| description | We report results on risk factors for invasive squamous cell and adenocarcinomas of the cervix in women aged 20-44 years from the UK National Case-Control Study of Cervical Cancer, including 180 women with adenocarcinoma, 391 women with squamous cell carcinoma and 923 population controls. The risk of both squamous cell and adenocarcinoma was strongly related to the lifetime number of sexual partners, and, independently, to age at first intercourse. The risk of both types of cervical cancer increased with increasing duration of use of oral contraceptives, and this effect was most marked in current and recent users of oral contraceptives. The risk of squamous cell carcinoma was associated with high parity and the risk of both squamous cell and adenocarcinoma increased with early age at first birth. Long duration smoking (20 or more years) was associated with a two-fold increase in the risk of squamous cell carcinoma, but smoking was not associated with the risk of adenocarcinoma. Further studies are needed to confirm the suggestion from this and other studies of differences in risk related to smoking between squamous cell and adenocarcinomas of the cervix. |
| first_indexed | 2024-03-06T21:28:15Z |
| format | Journal article |
| id | oxford-uuid:43d2679b-8c38-40a2-b97d-88f4f3636245 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T21:28:15Z |
| publishDate | 2003 |
| record_format | dspace |
| spelling | oxford-uuid:43d2679b-8c38-40a2-b97d-88f4f36362452022-03-26T14:57:47ZRisk factors for adenocarcinoma and squamous cell carcinoma of the cervix in women aged 20-44 years: the UK National Case-Control Study of Cervical Cancer.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:43d2679b-8c38-40a2-b97d-88f4f3636245EnglishSymplectic Elements at Oxford2003Green, JBerrington de Gonzalez, ASweetland, SBeral, VChilvers, CCrossley, BDeacon, JHermon, CJha, PMant, DPeto, JPike, MVessey, MWe report results on risk factors for invasive squamous cell and adenocarcinomas of the cervix in women aged 20-44 years from the UK National Case-Control Study of Cervical Cancer, including 180 women with adenocarcinoma, 391 women with squamous cell carcinoma and 923 population controls. The risk of both squamous cell and adenocarcinoma was strongly related to the lifetime number of sexual partners, and, independently, to age at first intercourse. The risk of both types of cervical cancer increased with increasing duration of use of oral contraceptives, and this effect was most marked in current and recent users of oral contraceptives. The risk of squamous cell carcinoma was associated with high parity and the risk of both squamous cell and adenocarcinoma increased with early age at first birth. Long duration smoking (20 or more years) was associated with a two-fold increase in the risk of squamous cell carcinoma, but smoking was not associated with the risk of adenocarcinoma. Further studies are needed to confirm the suggestion from this and other studies of differences in risk related to smoking between squamous cell and adenocarcinomas of the cervix. |
| spellingShingle | Green, J Berrington de Gonzalez, A Sweetland, S Beral, V Chilvers, C Crossley, B Deacon, J Hermon, C Jha, P Mant, D Peto, J Pike, M Vessey, M Risk factors for adenocarcinoma and squamous cell carcinoma of the cervix in women aged 20-44 years: the UK National Case-Control Study of Cervical Cancer. |
| title | Risk factors for adenocarcinoma and squamous cell carcinoma of the cervix in women aged 20-44 years: the UK National Case-Control Study of Cervical Cancer. |
| title_full | Risk factors for adenocarcinoma and squamous cell carcinoma of the cervix in women aged 20-44 years: the UK National Case-Control Study of Cervical Cancer. |
| title_fullStr | Risk factors for adenocarcinoma and squamous cell carcinoma of the cervix in women aged 20-44 years: the UK National Case-Control Study of Cervical Cancer. |
| title_full_unstemmed | Risk factors for adenocarcinoma and squamous cell carcinoma of the cervix in women aged 20-44 years: the UK National Case-Control Study of Cervical Cancer. |
| title_short | Risk factors for adenocarcinoma and squamous cell carcinoma of the cervix in women aged 20-44 years: the UK National Case-Control Study of Cervical Cancer. |
| title_sort | risk factors for adenocarcinoma and squamous cell carcinoma of the cervix in women aged 20 44 years the uk national case control study of cervical cancer |
| work_keys_str_mv | AT greenj riskfactorsforadenocarcinomaandsquamouscellcarcinomaofthecervixinwomenaged2044yearstheuknationalcasecontrolstudyofcervicalcancer AT berringtondegonzaleza riskfactorsforadenocarcinomaandsquamouscellcarcinomaofthecervixinwomenaged2044yearstheuknationalcasecontrolstudyofcervicalcancer AT sweetlands riskfactorsforadenocarcinomaandsquamouscellcarcinomaofthecervixinwomenaged2044yearstheuknationalcasecontrolstudyofcervicalcancer AT beralv riskfactorsforadenocarcinomaandsquamouscellcarcinomaofthecervixinwomenaged2044yearstheuknationalcasecontrolstudyofcervicalcancer AT chilversc riskfactorsforadenocarcinomaandsquamouscellcarcinomaofthecervixinwomenaged2044yearstheuknationalcasecontrolstudyofcervicalcancer AT crossleyb riskfactorsforadenocarcinomaandsquamouscellcarcinomaofthecervixinwomenaged2044yearstheuknationalcasecontrolstudyofcervicalcancer AT deaconj riskfactorsforadenocarcinomaandsquamouscellcarcinomaofthecervixinwomenaged2044yearstheuknationalcasecontrolstudyofcervicalcancer AT hermonc riskfactorsforadenocarcinomaandsquamouscellcarcinomaofthecervixinwomenaged2044yearstheuknationalcasecontrolstudyofcervicalcancer AT jhap riskfactorsforadenocarcinomaandsquamouscellcarcinomaofthecervixinwomenaged2044yearstheuknationalcasecontrolstudyofcervicalcancer AT mantd riskfactorsforadenocarcinomaandsquamouscellcarcinomaofthecervixinwomenaged2044yearstheuknationalcasecontrolstudyofcervicalcancer AT petoj riskfactorsforadenocarcinomaandsquamouscellcarcinomaofthecervixinwomenaged2044yearstheuknationalcasecontrolstudyofcervicalcancer AT pikem riskfactorsforadenocarcinomaandsquamouscellcarcinomaofthecervixinwomenaged2044yearstheuknationalcasecontrolstudyofcervicalcancer AT vesseym riskfactorsforadenocarcinomaandsquamouscellcarcinomaofthecervixinwomenaged2044yearstheuknationalcasecontrolstudyofcervicalcancer |