Granulocyte-Macrophage Colony-Stimulating Factor Regulates Effector Differentiation of Invariant Natural Killer T Cells during Thymic Ontogeny

Granulocyte-Macrophage Colony-Stimulating Factor Regulates Effector Differentiation of Invariant Natural Killer T Cells during Thymic Ontogeny

Invariant natural killer T (iNKT) cell-derived cytokines have important functions in inflammation, host defense, and immunoregulation. Yet, when and how iNKT cells undergo effector differentiation, which endows them with the capacity to rapidly secrete cytokines upon activation, remains unknown. We...

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Bibliographic Details
Main Authors:	Bezbradica, J, Gordy, L, Stanic, A, Dragovic, S, Hill, T, Hawiger, J, Unutmaz, D, Van Kaer, L, Joyce, S
Format:	Journal article
Language:	English
Published:	Cell Press 2006

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