Granulocyte-Macrophage Colony-Stimulating Factor Regulates Effector Differentiation of Invariant Natural Killer T Cells during Thymic Ontogeny
Invariant natural killer T (iNKT) cell-derived cytokines have important functions in inflammation, host defense, and immunoregulation. Yet, when and how iNKT cells undergo effector differentiation, which endows them with the capacity to rapidly secrete cytokines upon activation, remains unknown. We...
Main Authors: | Bezbradica, J, Gordy, L, Stanic, A, Dragovic, S, Hill, T, Hawiger, J, Unutmaz, D, Van Kaer, L, Joyce, S |
---|---|
Format: | Journal article |
Jezik: | English |
Izdano: |
Cell Press
2006
|
Podobne knjige/članki
-
Commitment toward the natural T (iNKT) cell lineage occurs at the CD4+8+ stage of thymic ontogeny
od: Bezbradica, JS, et al.
Izdano: (2005) -
Nur77 controls tolerance induction, terminal differentiation, and effector functions in semi-invariant natural killer T cells
od: Kumar, A, et al.
Izdano: (2020) -
Cutting Edge: The Ontogeny and Function of Va14Ja18 Natural T Lymphocytes Require Signal Processing by Protein Kinase Cθ and NF-κB
od: Stanic, AK, et al.
Izdano: (2004) -
Nur77 controls tolerance induction, terminal differentiation, and effector functions in NKT cells
od: Kumar, A, et al.
Izdano: (2020) -
Human natural killer T cells are heterogeneous in their capacity to reprogram their effector functions.
od: Karla A Eger, et al.
Izdano: (2006-12-01)