3-Azidoazetidines as the first scaffolds for β-amino azetidine carboxylic acid peptidomimetics: Azetidine iminosugars containing an acetamido group do not inhibit β-N-acetylhexosaminidases
Stable amides and oligopeptides derived from methyl . trans,trans-3-azido-4-hydroxymethyl-l-azetidine carboxylate, prepared in 19% yield from diacetone allose, is the first example of a β-amino-azetidine carboxylic acid incorporated into peptidomimetics and provides a scaffold for investigating seco...
Disgrifiad llawn
Manylion Llyfryddiaeth
| Prif Awduron: |
Liu, Z,
Jenkinson, S,
Kato, A,
Nakagawa, S,
Wormald, M,
Yu, C,
Fleet, G |
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| Fformat: | Journal article
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| Cyhoeddwyd: |
Elsevier
2016
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